Thymus Factor and Immunology

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The THYMUS FACTOR supplement is an innovative formula based on a complex composition developed through the latest scientific and technological solutions, combined with knowledge gained from years of experience. The manufacturer of the THYMUS FACTOR supplement is also responsible for the TFX® medication, which contains biologically active peptides isolated from carefully selected thymuses, meeting high medical standards in terms of quality and safety. TFX® has proven immunomodulatory effects and is recommended for patients with primary and secondary immunodeficiencies, as well as for cancer patients with a reduced immune response.

THYMUS FACTOR exhibits immunomodulatory effects, replacing the function of the thymus, which is essential for proper immune system function. Long-term use of this supplement has shown a beneficial impact on diseases associated with immunodeficiency—research has shown the presence of Thymosin alpha 1 and Thymosin Beta 4 in the thymus. The thymus plays an integrative role in the interaction of the nervous, hormonal, and immune systems.

Our thymus-based preparations are the result of Polish biotechnological innovation and represent 35 years of clinical research on thymus-derived preparations.

Summary of our team’s research findings on the effects of various thymus preparations:

The effects of different thymus preparations were evaluated on 3T3 fibroblast cells using the CellTiter Glo viability assay. Cells were incubated on a 96-well plate, and measurements were taken after 24 and 48 hours. Results were normalized against the untreated control. Three thymus preparations showed no toxicity at two high concentrations. The experiments will be repeated using lower concentrations of the preparations.

Splenocytes were isolated from 8-week-old mice, and the effects of thymus preparations on their viability were assessed using the CellTiter Glo 2.0 assay. No toxic effects were observed.

Thymocytes, isolated from 8-week-old mice, were incubated in various concentrations of the thymus preparation in culture medium for 24 hours. Hydrocortisone was then added at a concentration of 10 μg/ml. After one hour, cells were centrifuged, and the culture medium was discarded to remove hydrocortisone. Fresh medium (with or without the preparation) was added. After 24 hours, cell viability was measured using the CellTiter Glo 2.0 kit. A concentration of 10 μg/ml of the preparation demonstrated a protective effect on the cells.

The thymus preparations showed no toxicity and demonstrated protective effects for the cells.

Thymus preparations showed no toxicity and demonstrated protective effects on cells.

Selected Publications on Thymic Hormones

The role of thymic hormones in the treatment of COVID-19

Calf thymus hormones inhibit the growth of colon tumors (May 2022)

Melanoma treatment using thymosin – long-term impact on patients.

Analysis of the effects of thymic hormones on the treatment of malignant pleural effusion

Long-term impact of Thymosin Alpha 1 as an immunomodulatory therapy on the treatment of lung cancer patients (December 2021)